Bernhardt Trout: search on Z-Library

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1

Application of Continuous Crystallization in an Integrated Continuous Pharmaceutical Pilot Plant

Zhang, Haitao, Lakerveld, Richard, Heider, Patrick L., Tao, Mengying, Su, Min, Testa, Christopher J., D’Antonio, Alyssa N., Barton, Paul I., Braatz, Richard D., Trout, Bernhardt L., Myerson, Allan S.,

Journal:

Crystal Growth & Design

Year:

2014

Language:

english

File:

PDF, 2.92 MB

english, 2014

2

Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

Schaber, Spencer D., Gerogiorgis, Dimitrios I., Ramachandran, Rohit, Evans, James M. B., Barton, Paul I., Trout, Bernhardt L.

Journal:

Industrial & Engineering Chemistry Research

Year:

2011

Language:

english

File:

PDF, 1014 KB

english, 2011

3

Continuous Crystallization of Aliskiren Hemifumarate

Quon, Justin L., Zhang, Haitao, Alvarez, Alejandro, Evans, James, Myerson, Allan S., Trout, Bernhardt L.

Journal:

Crystal Growth & Design

Year:

2012

Language:

english

File:

PDF, 3.03 MB

english, 2012

4

Development of Continuous Crystallization Processes Using a Single-Stage Mixed-Suspension, Mixed-Product Removal Crystallizer with Recycle

Wong, Shin Yee, Tatusko, Adam P., Trout, Bernhardt L., Myerson, Allan S.

Journal:

Crystal Growth & Design

Year:

2012

Language:

english

File:

PDF, 2.30 MB

english, 2012

5

Regulatory Perspectives on Continuous Pharmaceutical Manufacturing: Moving from Theory to Practice September 26-27, 2016, International Symposium on the Continuous Manufacturing of Pharmaceuticals

Nasr, Moheb M., Krumme, Markus, Matsuda, Yoshihiro, Trout, Bernhardt L., Badman, Clive, Mascia, Salvatore, Cooney, Charles L., Jensen, Keith D., Florence, Alastair, Johnston, Craig, Konstantinov, Kons

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 458 KB

english, 2017

6

Achieving Continuous Manufacturing in Lyophilization: Technologies and Approaches

Pisano, Roberto, Arsiccio, Andrea, Capozzi, Luigi C., Trout, Bernhardt L.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2019

Language:

english

File:

PDF, 128 KB

english, 2019

7

Why We Need Continuous Pharmaceutical Manufacturing and How to Make It Happen

Badman, Clive, Cooney, Charles L., Florence, Alastair, Konstantinov, Konstantin, Krumme, Markus, Mascia, Salvatore, Nasr, Moheb, Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 158 KB

english, 2019

8

A screening tool for therapeutic monoclonal antibodies: Identifying the most stable protein and its best formulation based on thioflavin T binding

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Kurt Forrer, Prof. Bernhardt L. Trout

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

9

Aggregation in protein-based biotherapeutics: Computational studies and tools to identify aggregation-prone regions

Neeraj J. Agrawal, Sandeep Kumar, Xiaoling Wang, Bernhard Helk, Satish K. Singh, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

10

Developability index: A rapid in silico tool for the screening of antibody aggregation propensity

Timothy M. Lauer, Neeraj J. Agrawal, Naresh Chennamsetty, Kamal Egodage, Bernhard Helk, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 500 KB

english, 2012

11

Production and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing

Mao Wang, Gregory C. Rutledge, Allan S. Myerson, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 686 KB

english, 2012

12

Effects of Excipients on the Hydrogen Peroxide-Induced Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor

Jin Yin, Jhih-Wei Chu, Margaret Speed Ricci, David N. Brems, Daniel I. C. Wang, Bernhardt L. Trout

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

13

Aggregation-Prone Motifs in Human Immunoglobulin G

Naresh Chennamsetty, Bernhard Helk, Vladimir Voynov, Veysel Kayser, Bernhardt L. Trout

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 2.45 MB

english, 2009

14

Role of Arginine in the Stabilization of Proteins against Aggregation †

Baynes, Brian M., Wang, Daniel I. C., Trout, Bernhardt L.

Journal:

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

15

Effect of Particle Size on the Adsorption of O and S Atoms on Pt: A Density-Functional Theory Study

Lin, Xi, Ramer, Nicholas J., Rappe, Andrew M., Hass, Kenneth C., Schneider, William F., Trout, Bernhardt L.

Journal:

Journal of Physical Chemistry B

Year:

2001

Language:

english

File:

PDF, 153 KB

english, 2001

16

Surface Design for Controlled Crystallization: The Role of Surface Chemistry and Nanoscale Pores in Heterogeneous Nucleation

Diao, Ying, Myerson, Allan S., Hatton, T. Alan, Trout, Bernhardt L.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.90 MB

english, 2011

17

Mathematical modeling and design of layer crystallization in a concentric annulus with and without recirculation

Zhou, Lifang, Su, Min, Benyahia, Brahim, Singh, Aniruddh, Barton, Paul I., Trout, Bernhardt L., Myerson, Allan S., Braatz, Richard D.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

18

Use of Continuous MSMPR Crystallization with Integrated Nanofiltration Membrane Recycle for Enhanced Yield and Purity in API Crystallization

Ferguson, Steven, Ortner, Franziska, Quon, Justin, Peeva, Ludmila, Livingston, Andrew, Trout, Bernhardt L., Myerson, Allan S.

Journal:

Crystal Growth & Design

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

19

Development of Continuous Anti-Solvent/Cooling Crystallization Process using Cascaded Mixed Suspension, Mixed Product Removal Crystallizers

Zhang, Haitao, Quon, Justin, Alvarez, Alejandro J., Evans, James, Myerson, Allan S., Trout, Bernhardt

Journal:

Organic Process Research & Development

Year:

2012

Language:

english

File:

PDF, 4.61 MB

english, 2012

20

Polymorphic control by heterogeneous nucleation - A new method for selecting crystalline substrates

Chadwick, Keith, Myerson, Allan, Trout, Bernhardt

Journal:

Year:

2011

Language:

english

File:

PDF, 174 KB

english, 2011

21

Phase diagram of oxygen adsorbed on platinum (111) by first-principles investigation

Tang, Hairong, Van der Ven, Anton, Trout, Bernhardt L.

Journal:

Physical Review B

Year:

2004

Language:

english

File:

PDF, 534 KB

english, 2004

22

Rational Design of Biobetters with Enhanced Stability

Courtois, Fabienne, Schneider, Curtiss P., Agrawal, Neeraj J., Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 516 KB

english, 2015

23

Achieving Continuous Manufacturing May 20–21 2014 Continuous Manufacturing Symposium

Badman, Clive, Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 44 KB

english, 2015

24

Continuous Crystallization of Cyclosporine: Effect of Operating Conditions on Yield and Purity

Li, Jicong, Lai, Tsai-ta C., Trout, Bernhardt L., Myerson, Allan S.

Journal:

Crystal Growth & Design

Year:

2017

Language:

english

File:

PDF, 880 KB

english, 2017

25

Development of Maltodextrin Based Immediate Release Tablets using an Integrated Twin-Screw Hot Melt Extrusion and Injection Molding Continuous Manufacturing Process

Puri, Vibha, Brancazio, Dave, Desai, Parind M., Jensen, Keith D., Chun, Jung-Hoon, Myerson, Allan S., Trout, Bernhardt L.

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 677 KB

english, 2017

26

Integrated hot-melt extrusion − injection molding continuous tablet manufacturing platform: Effects of critical process parameters and formulation attributes on product robustness and dimensional stability.

Desai, Parind M., Hogan, Rachael C., Brancazio, David, Puri, Vibha, Jensen, Keith D., Chun, Jung-Hoon, Myerson, Allan S., Trout, Bernhardt L.

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

27

From batch to continuous: freeze-drying of suspended vials for pharmaceuticals in unit-doses

Capozzi, Luigi Carlo Carlo, Trout, Bernhardt L, Pisano, Roberto

Journal:

Industrial & Engineering Chemistry Research

Year:

2019

Language:

english

File:

PDF, 7.47 MB

english, 2019

28

Understanding the Role of Preferential Exclusion of Sugars and Polyols from Native State IgG1 Monoclonal Antibodies and its Effect on Aggregation and Reversible Self-Association

Sudrik, Chaitanya M., Cloutier, Theresa, Mody, Neil, Sathish, Hasige A., Trout, Bernhardt L.

Journal:

Pharmaceutical Research

Year:

2019

Language:

english

File:

PDF, 3.04 MB

english, 2019

29

Molecular computations of preferential interaction coefficients of IgG1 monoclonal antibodies with sorbitol, sucrose, and trehalose and the impact of these excipients on aggregation and viscosity

Cloutier, Theresa, Sudrik, Chaitanya, Mody, Neil, Sathish, Hasige A., Trout, Bernhardt L

Journal:

Molecular Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 1.83 MB

english, 2019

30

Molecular computations of preferential interaction coefficients of IgG1 monoclonal antibodies with sorbitol, sucrose, and trehalose and the impact of these excipients on aggregation and viscosity

Cloutier, Theresa, Sudrik, Chaitanya, Mody, Neil, Sathish, Hasige A., Trout, Bernhardt L

Journal:

Molecular Pharmaceutics

Year:

2019

File:

PDF, 1.83 MB

2019

31

A comprehensive picture of non-site specific oxidation of methionine residues by peroxides in protein pharmaceuticals

Jhih-Wei Chu, Jin Yin, Bernard R. Brooks, Daniel I.C. Wang, Margaret Speed Ricci, David N. Brems, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

32

Evaluation of a non-arrhenius model for therapeutic monoclonal antibody aggregation

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Kurt Forrer, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 720 KB

english, 2011

33

Solid-state NMR characterization of high-loading solid solutions of API and excipients formed by electrospinning

Blair Brettmann, Erin Bell, Allan Myerson, Bernhardt Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 276 KB

english, 2012

34

Application of transition path sampling methods in catalysis: A new mechanism for bond formation in the methanol coupling reaction in chabazite

Cynthia S. Lo, Ravi Radhakrishnan, Bernhardt L. Trout

Journal:

Catalysis Today

Year:

2005

Language:

english

File:

PDF, 778 KB

english, 2005

35

Diffusion and reaction in ZSM-5 studied by dynamic Monte Carlo

Bernhardt L. Trout, Arup K. Chakraborty, Alexis T. Bell

Journal:

Chemical Engineering Science

Year:

1997

Language:

english

File:

PDF, 795 KB

english, 1997

36

The interaction of HCl with the (0 0 0 1) face of hexagonal ice studied theoretically via Car–Parrinello molecular dynamics

Yves A. Mantz, Franz M. Geiger, Luisa T. Molina, Mario J. Molina, Bernhardt L. Trout

Journal:

Chemical Physics Letters

Year:

2001

Language:

english

File:

PDF, 340 KB

english, 2001

37

The dissociation mechanism of H2O in water studied by first-principles molecular dynamics

Bernhardt L Trout, Michele Parrinello

Journal:

Chemical Physics Letters

Year:

1998

Language:

english

File:

PDF, 85 KB

english, 1998

38

A method to extract potentials from the temperature dependence of Langmuir constants for clathrate-hydrates

Martin Z. Bazant, Bernhardt L. Trout

Journal:

Physica A: Statistical Mechanics and its Applications

Year:

2001

Language:

english

File:

PDF, 280 KB

english, 2001

39

Prediction of protein binding regions

Naresh Chennamsetty, Vladimir Voynov, Veysel Kayser, Bernhard Helk, Bernhardt L. Trout

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2011

Language:

english

File:

PDF, 746 KB

english, 2011

40

Tryptophan-Tryptophan Energy Transfer and Classification of Tryptophan Residues in Proteins Using a Therapeutic Monoclonal Antibody as a Model

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Bernhard Helk, Bernhardt L. Trout

Journal:

Journal of Fluorescence

Year:

2011

Language:

english

File:

PDF, 717 KB

english, 2011

41

Effects of Antioxidants on the Hydrogen Peroxide-Mediated Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor and Human Parathyroid Hormone Fragment 13-34

Jin Yin, Jhih-Wei Chu, Margaret Speed Ricci, David N. Brems, Daniel I. C. Wang, Bernhardt L. Trout

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

42

Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, Kurt Forrer, Bernhard Helk, Professor Bernhardt L. Trout

Journal:

Biotechnology Journal

Year:

2011

Language:

english

File:

PDF, 718 KB

english, 2011

43

Mechanisms of Protein Stabilization and Prevention of Protein Aggregation by Glycerol

Vagenende, Vincent, Yap, Miranda G. S., Trout, Bernhardt L.

Journal:

Year:

2009

Language:

english

File:

PDF, 3.21 MB

english, 2009

44

A general set of order parameters for molecular crystals

Santiso, Erik E., Trout, Bernhardt L.

Journal:

The Journal of Chemical Physics

Year:

2011

Language:

english

File:

PDF, 2.17 MB

english, 2011

45

Solid-state nuclear magnetic resonance study of the physical stability of electrospun drug and polymer solid solutions

Blair Kathryn Brettmann, Allan S. Myerson, Bernhardt L. Trout

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 368 KB

english, 2012

46

Molecular level insight into intra-solvent interaction effects on protein stability and aggregation

Diwakar Shukla, Curtiss P. Schneider, Bernhardt L. Trout

Journal:

Advanced Drug Delivery Reviews

Year:

2011

Language:

english

File:

PDF, 655 KB

english, 2011

47

Density-functional theory characterization of acid sites in chabazite

Cynthia Lo, Bernhardt L. Trout

Journal:

Journal of Catalysis

Year:

2004

Language:

english

File:

PDF, 1.02 MB

english, 2004

48

A consistent and verifiable macroscopic model for the dissolution of liquid CO2 in water under hydrate forming conditions

Ravi Radhakrishnan, Alexander Demurov, Howard Herzog, Bernhardt L Trout

Journal:

Energy Conversion and Management

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

49

Free Energy of Binding of a Small Molecule to an Amorphous Polymer in a Solvent

Chunsrivirot, Surasak, Trout, Bernhardt L.

Journal:

Year:

2011

Language:

english

File:

PDF, 6.34 MB

english, 2011

50

Complex Interactions between Molecular Ions in Solution and Their Effect on Protein Stability

Shukla, Diwakar, Schneider, Curtiss P., Trout, Bernhardt L.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 838 KB

english, 2011